What Is Prague Criteria?

By Robert Palmer

The Prague Criteria is a set of guidelines used to classify endoscopic findings in the esophagus. These criteria were first established in 2006 at the Prague C & M Workshop, hence the name.

The primary objective of these criteria is to standardize the evaluation and reporting of Barrett’s esophagus and its associated dysplasia. They help physicians accurately diagnose and monitor patients with this condition.

The Prague Criteria are based on two main factors: the length of the Barrett’s segment and the presence or absence of dysplasia. Let’s take a closer look at each factor.

Barrett’s Esophagus Length
The length of the Barrett’s segment is determined by measuring the distance between two landmarks in the esophagus – typically, the gastroesophageal junction and the proximal margin of visible Barrett’s mucosa. The measurement is then recorded in centimeters.

According to the Prague Criteria, there are four categories for defining Barrett’s esophagus length:

  • M: Maximum extent
  • C: Circumferential involvement
  • MP: Maximum extent plus circumferential involvement
  • OP: Other circumferential involvement

Dysplasia Presence or Absence
Dysplasia refers to abnormal cells that have potential to become cancerous. The presence or absence of dysplasia in a patient with Barrett’s esophagus is an important factor that influences their management plan.

The Prague Criteria provide five categories for classifying dysplasia:

  • NDBE: No Dysplasia but indefinite for Dysplasia
  • HGD: High Grade Dysplasia (with or without intramucosal carcinoma)
  • IMC: Intramucosal Carcinoma (without dysplasia)
  • EC: Esophageal Carcinoma

Conclusion

In conclusion, the Prague Criteria are an essential tool for physicians to diagnose and manage patients with Barrett’s esophagus. These criteria provide a standardized approach to evaluate and report the endoscopic findings, which helps in accurate diagnosis and follow-up of patients.

If you have been diagnosed with Barrett’s esophagus or any other gastrointestinal condition, it is important to work closely with your healthcare provider for proper management and treatment.