How Does Sedation Vacation Prevent VAP?

By Anna Duncan

Sedation vacation is a strategy used in the intensive care unit (ICU) to prevent ventilator-associated pneumonia (VAP). VAP is a lung infection that occurs in patients who are on mechanical ventilation. Patients on mechanical ventilation are at a higher risk of developing pneumonia due to various factors such as impaired cough reflex, impaired immune system, and colonization of bacteria in the respiratory tract.

One of the main causes of VAP is prolonged sedation. When patients are sedated for extended periods, they are unable to cough effectively and clear their airways, which allows bacteria to grow and cause infections. Sedation vacation is a strategy that involves interrupting sedative therapy for a period of time to assess the patient’s level of consciousness and ability to breathe spontaneously.

During a sedation vacation, patients are woken up from sedation and allowed to breathe on their own with or without the support of mechanical ventilation. This allows healthcare providers to assess the patient’s level of consciousness, breathing effort, and ability to protect their airway. If the patient demonstrates adequate respiratory effort and can protect their airway, they may be extubated and taken off mechanical ventilation.

Sedation vacation has been shown to reduce the duration of mechanical ventilation, shorten ICU stay, lower rates of delirium, and decrease rates of VAP. By interrupting prolonged sedation therapy, patients have improved cough reflexes and better control over their airways. This reduces the risk of colonization by harmful bacteria that can lead to infections such as VAP.

In addition to interrupting sedative therapy, other measures can be taken to prevent VAP in mechanically ventilated patients. These include elevating the head of the bed at an angle greater than 30 degrees, practicing good hand hygiene by healthcare providers when caring for patients on mechanical ventilation, providing daily oral care with antiseptic mouthwash, using endotracheal tubes with subglottic suction ports, and administering stress ulcer prophylaxis to prevent gastrointestinal bleeding.

In conclusion, sedation vacation is a strategy used in the ICU to prevent VAP. Interrupting prolonged sedation therapy improves cough reflexes and airway protection, reducing the risk of colonization by harmful bacteria that can cause infections such as VAP. This, combined with other preventative measures, can significantly reduce the incidence of VAP and improve patient outcomes.